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Exercise-Induced Collapse (EIC) in Labradors

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Adult chocolate Labrador on a beach at sunset with a tennis ball in its mouth
Photo by Reed Naliboff on Unsplash
On this page (7)
  1. Quick answers
  2. What EIC looks like
  3. What to do during an episode
  4. The genetics
  5. Living with an affected Lab
  6. FAQ
  7. Sources

Quick answers

What is EIC in Labs?

Exercise-Induced Collapse is an inherited neuromuscular condition in Labs. Affected dogs can become wobbly or collapse after intense exercise, then usually recover within minutes of rest. DNA testing identifies carriers and affected dogs, and responsible breeders avoid breeding two carriers together. Answer page →

What EIC looks like

An affected Lab is typically young (often 5 months to 3 years) and fit. After 5–20 minutes of intense, exciting exercise like retrieving, hunting or repeated ball throws, its hind legs become wobbly and then weak. The dog may drag its back legs while staying alert and still wanting to play. Most recover within about 5–25 minutes (University of Minnesota).

What to do during an episode

  1. Stop all exercise immediately. Don’t throw “one more”.
  2. Keep the dog calm and cool. Body temperature rises in these episodes.
  3. Call your vet if recovery is slow, if the dog seems confused, or if it’s the first episode. Other conditions (heatstroke, heart disease, low blood sugar) can look similar.

The genetics

Researchers at the University of Minnesota identified a mutation in the DNM1 gene (Patterson et al., 2008).

DNA resultMeaning
Clear (N/N)Won’t have EIC from this mutation
Carrier (N/EIC)Not expected to collapse; can pass it on
Affected (EIC/EIC)At risk of episodes

OFA’s CHIC program for Labradors includes an EIC DNA test. Ask any breeder for it (breeder checklist). Consumer DNA kits like Embark also screen for it.

Living with an affected Lab

Many EIC/EIC dogs live normal lives with management:

  • Avoid prolonged, frenzied retrieving, especially in heat.
  • Swap in calmer activities: steady walks, swimming with breaks, scent work.
  • Learn the dog’s early signs and stop before them.

Frequently asked questions

Is EIC fatal?

Most affected dogs recover within about 5–25 minutes of rest, but deaths during episodes have been reported. Stop exercise at the first sign of wobbling.

Can a carrier Lab get EIC?

EIC is autosomal recessive: dogs with two copies of the mutation are at risk; carriers (one copy) are not expected to collapse.

Sources

  1. Patterson et al. 2008, A canine DNM1 mutation is highly associated with the syndrome of exercise-induced collapse (Nature Genetics)
  2. University of Minnesota: Exercise Induced Collapse in Labrador Retrievers
  3. OFA: Labrador Retriever CHIC requirements (EIC DNA test)

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